While visiting Jim's house, the group discovers that his parents have committed suicide. Jim learns that while he was comatose, a virus had spread uncontrollably among the populace, turning them into vicious, mindless, blood-spewing monsters (referred to as 'The Infected'), resulting in societal collapse, possibly on a global scale. Taking refuge in a church, Jim is chased by some of London's now Rage infected residents, but fortunately for Jim he runs into and is rescued by two survivors, Selena (Naomie Harris) and Mark (Noah Huntley), who rush him to their hideout in a section of the London Underground.
However he soon discovers the abandoned streets are rife with catastrophe. Upon leaving the hospital, he discovers that London's streets are much like the hospitals, empty. Jim explores the abandoned hospital only to find no one is around. Twenty-eight days later, a bicycle courier named Jim (Cillian Murphy) awakens from a coma in a deserted hospital. The Virus has been introduced to Chimpanzee's in a research facility later when an infected chimpanzee bites a naive animal rights activist attempting to free it from a laboratory the chaos begins. The plot opens with the initial outbreak of the 'Rage virus'.
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